The 5th FSEV meeting 2022
Après deux années à échanger par écrans interposés, nous sommes impatients de pouvoir réunir la communauté des EVologistes lors d’un congrès en présentiel. Pour l’occasion la FSEV (Société Française des Vésicules Extracellulaires) s’associe à l’AFC (Association Française de Cytométrie) pour organiser un congrès à Paris du 19 au 21 octobre 2022. Ce congrès vous proposera un après-midi dédié à l’apport de la technologie de Cytométrie en flux dans l’étude des vésicules extracellulaires. Suivront ensuite deux jours de sessions plénières, de présentations orales et de posters qui vous donneront un aperçu de la vitalité et de l’excellence de la recherche française sur les vésicules extracellulaires. Nous espérons vous y voir nombreux !
Les comités organisateurs de la FSEV et de l’AFC.
FSEV 2022 Invited speakers
André
Görgens
KI, Stockolm, Sweden
André Görgens obtained his PhD in hematopoietic stem cell biology at the University Hospital Essen in the lab of Prof. Bernd Giebel. Afterwards, he became more and more interested in intercellular communication through extracellular vesicles. He is currently Researcher in the lab of Samir El Andaloussi at Karolinska Institutet (Stockholm, Sweden), working on developing Flow Cytometry based assays to ultimalty understand and exploit Extracellular Vesicle heterogeneity for advancement of therapy and diagnostics.
Edwin
van der Pol
Amsterdam University Medical centers
Edwin van der Pol is interested in the detection of extracellular vesicles as biomarkers for disease. He is scientist at the department of Biomedical engineering and Physics and the Laboratory of Experimental Clinical Chemistry in the Amsterdam University Medical Centers, The Netherlands. He is also co-founder of the company Exometry, which applies physics to understand and push the technological limits involved in vesicle detection.
Clotilde
Théry
Institut Curie Paris, France
Dr. Clotilde Théry is research director (DR1) at INSERM, working at Institut Curie in Paris, where she heads the team « Extracellular Vesicles, Immune responses and Cancer », within Unit INSERM U932 “Immunology and Cancer”.Her goals are to understand the physiological functions of EV secretion during an in vivo immune response and during tumor growth, and her approach is to continuously go from basic cell biology questions on their modes of formation to application of this knowledge to in vivo situations.
She has organized several symposia and sessions dedicated to exosomes in international meetings, and in particular a first “International Workshop on Exosomes” in Institut Curie, in Paris, in 2011, which led to the creation of the International Society for Extracellular Vesicles (ISEV), for which she served as Secretary General from 2012 to 2016, and President from 2020 to 2022.
Céline
Eli Caille
FEMTO-ST, Besançon, France
Céline ELIE-CAILLE obtained her Ph.D degree in enzymatic engineering from the University of Technology of Compiègne (UTC, France) in 2003. After a post-doctoral position at the BIOTEC Institute in Dresden (Germany) in 2004-2006 where she acquired skills in atomic force microscopy (in Daniel Mueller’s lab), she joined the FEMTO-ST Institute (UMR6174 CNRS) in Besancon (France), as an associate professor in 2006. In the MicroNanoSciences and Systems research department she is coleading. Since 2013, she focuses her research onto extracellular vesicles qualification, and how to combine analytical and multiscale characterization platforms for their quantification and qualification, in biological media.
Julie
Gavard
CRCI2NA, Nantes, France
Julie Gavard received her PhD from University Pierre Marie Curie for her work on cell-cell adhesion at the neuromuscular junctions (2004). She joined the NIH in Silvio Gutkind’ lab and discovered the molecular mechanisms by which angiogenic factors modulate the endothelial barrier (2005-08). In 2008, she was appointed permanent researcher at CNRS and rapidly established an independent team at the Institute Cochin, Paris. In 2012, Julie Gavard was given the honorary Bronze Medal from CNRS. In 2015, she moved to Nantes in the Cancer & Immunology Research Center. Her team ’Signaling in Oncogenesis, Angiogenesis, and Permeability”, SOAP, explores how intracellular signaling pathways and extracellular communication are enslaved for the benefit of tumor cell survival and expansion.
Nicolas
Soler
Université de Lorraine, Nancy, France
Nicolas Soler is interested in understanding the evolution of bacterial genomes and the biology of mobile genetic elements. During his PhD, he studied extracellular vesicles of hyperthermophilic archaea, which made him aware of the diversity of biological roles of EVs in microbiology. Recently, he proposed a new concept for EV-mediated horizontal gene transfer, called vesiduction
Sophie
Rome
CarMen, Lyon, France
Sophie Rome is Research Director at the CarMeN laboratory which works in the field of metabolic diseases and nutrition in Lyon. After a thesis in microbial ecology, phylogeny and bioinformatics, and two post-docs (Australia, UWA, and Singapore, IMCB) she was recruited at INRAe Institut in the department of Human Nutrition, in 2007 with a permanent position, to work on the molecular mechanisms involved in the development of muscle insulin resistance during obesity and type 2 diabetes. For more than 10 years, she has been working on the cross-talks between skeletal muscle and insulin-sensitive tissues via extracellular vesicles and she has demonstrated the role of these vesicles in the muscle-pancreas and muscle-adipose tissue dialogues in the control of glucose homeostasis, and as endocrine signals to control myogenesis and muscle mass.In parallel, she is studying the role of extracellular vesicles from plants on intestinal physiology and on the immune response in order to determine their therapeutic potential in the treatment of nutrition-related diseases. She has participated in the creation of the FSEV and was its president until 2022. In parallel, she was co-chair of the international committee for the organization of the ISEV annual meeting in 2021 (virtual) and 2022 (Lyon).
éric
Rubinstein
CIMI, Paris
Éric Rubinstein is a research director at Inserm and currently works at the Center for Immunology and Infectious Diseases in Paris (CIMI, Inserm/CNRS/Sorbonne University). After a degree in veterinary medicine, and an internship at the University of Tennessee in the laboratory of Roger Carroll, he completed a PhD under the supervision of Claude Boucheix at Inserm U268 in Villejuif. Shortly after the cloning of the first tetraspanins, which defined a new family of proteins of unknown function, he aimed at understanding their biological function by searching for associated molecules. After showing that tetraspanins associate with each other and with a same set of integral proteins, he coined the concept of the tetraspanin web, which refers to a dynamic network of interaction formed by these molecules, and led to the idea that tetraspanins play a role in membrane compartmentalization. Subsequently, he and his team analyzed the repertoire of tetraspanin-associated proteins by mass spectrometry, unraveled a subset of direct interactions in the tetraspanin web, and identified a set of 6 closely related tetraspanins that associate directly with and regulate the trafficking and function of the metalloprotease ADAM10, thereby playing a role in Notch signaling. With Claude Boucheix and Stéphanie Charrin, he contributed to the identification of CD9 and CD81 as membrane proteins required for sperm-egg fusion that, in contrast, play a negative role in muscle cell fusion. A collaboration with Olivier Silvie and Dominique Mazier led to the identification of CD81 as the first hepatocyte protein required for hepatocyte infection by the malaria parasite.